After thinking about this for a second, it totally makes sense. Word is that Ryan Seacrest is tapped to take Regis Philbin's place on Live when he retires.
Regis is about to celebrate his twentieth anniversary on the show, and it's time for a change! Of course this would mean a humungo contract for Ryan, but Regis isn't doing too bad in the paycheck department, so it wouldn't be a huge hit on the show.
Ryan is so great on the radio, and it seems like his days at E! News are numbered, just based on his lack of interest in the topics. Maybe a move to the Big Apple is just what Ry Guy needs! Do you think he'd gel with Kelly as a co-host?