Penn, who plays Dan Humphrey on the hit show, admits the job has grown stale.
He tells the New York Post he's keen to move on, stating, "It is what it is. It's the fourth season. It's become routine."
And routine isn't the only reason he's thinking of leaving the show, apparently him and real life girlfriend Blake Lively have beef with co-stars Ed Westwick and Jessica Szohr, who play Chuck and Vanessa on the show.
He adds, "We're not friends. I mean we just don't double date."
Hmm trouble in paradise for one of the biggest shows on TV? This doesn't sound good! If Penn were to leave the show, do you he's be missed? Or can his character Dan disappear and the show will carry on without a problem?