Nicollette Sheridan and David Spade Hookup!

 Image by PR Photos

Talk about an odd couple! 'Desperate Housewives' star Nicollette Sheridan was spotted sucking face with David Spade during her 45th birthday party at Hotspot Luau.

"They cuddled and kissed," says an onlooker. "They were full-on making out in a booth."

David Spade? Really Nicollette? What is his appeal? We just don't get it! Maybe it was a drunken hookup? Whatever the case is, let's hope it was a temporary fix.